A Research Study On Calcium Dependent Cytosolic Rat Brains...

Calpain was first discovered within the brain, lens of eyes and other tissues by Gordon Guroff in 1964. This was done by isolating enzymes in both rat brains and skeletal muscles. These findings concluded that Calpains are calcium-dependent cytosolic cysteine proteinases. With further research, it was noted that Calpains are found in nearly all eukaryotes as well as some types of bacteria but, not within archaebacterial domain. Structurally, Calpains contain four functional domains with two domains that serve as regulatory subunits. In general, Calpains have multiple functions such as cell cycle progression, cell differentiation, membrane fusion, signal transduction, membrane fusion, apoptosis and myogenesis (Khorchid Mitsuhiko, 2002).†¦show more content†¦Only a few classical Calpains have been identified within invertebrates. Specifically for human Calpain genes, there are nine classical Calpains and six non-classical Calpains, giving a total of 15 Calpain genes for human s. For human Calpain genes, there two genes for regulatory subunits and one specific inhibitor protein. Classical Calpains, especially those found in humans, are ubiquioltly expressed and are controlled through the inhibitor of Calpastain (Trinchese et al., 2008). Although the role of calcium inducing change to enable Calpastatin to bind to Calpain is unknown, it is seen that Calpain 2 is bounded by inhibitory domains of Calpastatin which are inhibiting Calpain from both sides of the active site cleft. From this it was assumed that Calpastatin not only recognizes that there are multiple lower affinity sites but, that they are only present in the calcium-bound form of the enzyme which results in the interaction between Calpain and Calpastatin to be tight, specific and calcium dependent (Hanna, Campbell, Davies, 2008). Aside from Calpains causing cells to migrate, differentiate, proliferate and die, activation of Calpains have been linked to the pathogenesis of Alzheimer’s Disease. 5 million individuals have been diagnosed with Alzheimer’s Disease with an increase of 68 percent from 2000-2010, making it the sixth leading cause of death within

Pi foods solution Free Essays

Suggestions to resolve the problem regarding the irregular visit of the sales person to the C and D class Retailers and Shortage of supplies to the distributors. Irregular visit of the salesperson: a) We can give good amount of Incentives to the salesperson who visit the C and D class Retailers 2, 3 times in a week. B) We can also make a minimum visit criteria which Is must for every salesperson, for E. We will write a custom essay sample on Pi foods solution or any similar topic only for you Order Now . Every salesperson must veils the C and D class retailers minimum 2 times In a week. C) The more the salesman sold the reduces to the C and D class retailers the more Good Incentives he will get For E. G. We will also give him free tickets to Movies or If he performs very well than we can give him a free International tour, In this way the salesperson gets motivated and they start visiting the c and D class retailers more often. Shortage of supplies to the Distributors a) Difference in Forecasted sales figures and the Factory production figures is happened every time, because most of the time the production capacity of the factory s limited and it cannot be extended immediately as it involves high cost and additional equipment’s to increase the production, so when this problem arrives when forecasted sales figures doesn’t match the factory production figures in that case company can make a policy in which it can explain that our production capacity is only this For E. G. E can only produce 100 cigarette’s in a week or our production capacity is limited to only 100 cigarettes per week and this policies can be explained o the C and D class retailers, that we can only supply 100 cigarette’s in a week not more than that but we can give you special discount if u buy from us or we can supply u these cigarette’s at a cheap rate than anyone else in the market in that case retailers will buy the cigarette’s despite of the Sales forecast that shows 200 cigarettes is going to sold this week but only 100 cigarettes are supplied. In this way we can resolve the mismatch problem of sales forecast and Factory production figures. ) We can clearly explain the production capacity to the retailers, that our production capacity is only this, but we can give u special discount If u buy from us. In this way the retailers will buy from us despite of what there Sales forecast says. A) We can give good amount of incentives to the salesperson who visit the C and D which is must for every salesperson, for E. G. Every salesperson must visit the C and D class retailers minimum 2 times in a week. ) The more the salesman sold the reduces to the C and D class retailers the more Good incentives he will get For E. G. We will also give him free tickets to Movies or if he performs very well than we can give him a free international tour, in this way the salesperson gets motivated and they start visiting the C and D class retailers more often. A) Difference in Forecasted sales figures and the Factory production figures is when foreca sted sales figures doesn’t match the factory production figures in that capacity is only this, but we can give u special discount if u buy from us. How to cite Pi foods solution, Essays

Charade in Gaza and the West Bank Essay Example For Students

Charade in Gaza and the West Bank Essay While going over video and hundreds of photographs depicting the Israeli army evict Jewish settlers from Gaza and the West Bank, I suddenly understood the legendary Jewish predilection to exaggerate. Some Jews were actually smiling as they were being dragged from their homes while others cried. Some were laughing in the background. Others, mostly women, put on a melodramatic display of emotion similar to what one might see in a musical. The photographic exploitation of the unenlightened consternation on the faces of adolescents was particularly distasteful. Comparing these images to international scenes of oppression by various authoritarian and despotic regimes such as China, Russia, or Latin America, complete with armed police tear gas and riot gear, the settler disengagement struck me as a well orchestrated charade that without serious injury went off like clockwork: uncharacteristic of the more unpredictable circumstances one might expect from a resistance. Some settlers seemed more concerned about participating in the event than being uprooted. To be there for the occasion, so they can fill their lives with meaning and tell their children about the terrible atrocity that happened in the summer of 2005. Of all the Nazi-era films I have scene, I do not recall any where Jews and Nazis hugged each other before we were led away to the gas chambers. Furthermore, the Israeli government is handsomely reimbursing the settlers for their efforts. It is a damn shame that some Jews would even think of comparing the disengagement to the Nazi era! I am sure fundamentalist Jews will write books about The Israeli Betrayal, Horror In Gaza, Shoah in the West Bank, etc, while inventing charities and organizations to commemorate the new Holocaust. This will not be tolerated by American Jews who donate money to Israel. We will no longer be duped by religious fundamentalist propaganda and land grabbers. Trouble makers will be kept in their place. The Warsaw Ghetto Uprising lasted twenty seven days with approximately one thousand fighters and many fatalities before it was crushed. The disengagement lasted a few days with thousands upon thousands of settlers hugging their oppressors without serious injury. Where is the comparison? Mordechaj Anielewicz would turn over in his grave if he caught wind of the comparison some Jews are making between the Nazi era and the charade in Gaza and the West Bank. Wearing a yellow star of David on ones chest in reminiscence of Nazi era atrocities during the disengagement is to devalue the Holocaust! Shame on you!! American Jews are sick and tired of Jewish fundamentalist propaganda. We hear about Arabs who raise their children to hate Jews. It is true that a lot do, but what about Jews who raise their children to hate Arabs? What about Jews who preach Torah down the barrel of a rifle? What about Jews who make the fundamentalist claim that God gave us the land? And how is it possible to make a distinction between Islamofascists, and Jewish fascists? What is the difference between Baruch Goldstein and Mohammad Atta? American Jews will no longer be tricked by fundamentalist Rabbis and religious intellectuals who attempt to pull at the heart-strings of American Jews, seducing them with devices such as the right of return, the Golah, obligation, etc. The David and Goliath motif is old news. You need to get a life. You need to mingle. How is it that Gods chosen got themselves into a position where we subjugate and oppress an entire Palestinian people in the first place? Is that what God chose for us to do? Is this what Rashi meant when he said He created it and he gave it to them, and by His wish He took it from them and gave it to us? .uf67cce27fcdf147f87179a4f0751ff39 , .uf67cce27fcdf147f87179a4f0751ff39 .postImageUrl , .uf67cce27fcdf147f87179a4f0751ff39 .centered-text-area { min-height: 80px; position: relative; } .uf67cce27fcdf147f87179a4f0751ff39 , .uf67cce27fcdf147f87179a4f0751ff39:hover , .uf67cce27fcdf147f87179a4f0751ff39:visited , .uf67cce27fcdf147f87179a4f0751ff39:active { border:0!important; } .uf67cce27fcdf147f87179a4f0751ff39 .clearfix:after { content: ""; display: table; clear: both; } .uf67cce27fcdf147f87179a4f0751ff39 { display: block; transition: background-color 250ms; webkit-transition: background-color 250ms; width: 100%; opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #95A5A6; } .uf67cce27fcdf147f87179a4f0751ff39:active , .uf67cce27fcdf147f87179a4f0751ff39:hover { opacity: 1; transition: opacity 250ms; webkit-transition: opacity 250ms; background-color: #2C3E50; } .uf67cce27fcdf147f87179a4f0751ff39 .centered-text-area { width: 100%; position: relative ; } .uf67cce27fcdf147f87179a4f0751ff39 .ctaText { border-bottom: 0 solid #fff; color: #2980B9; font-size: 16px; font-weight: bold; margin: 0; padding: 0; text-decoration: underline; } .uf67cce27fcdf147f87179a4f0751ff39 .postTitle { color: #FFFFFF; font-size: 16px; font-weight: 600; margin: 0; padding: 0; width: 100%; } .uf67cce27fcdf147f87179a4f0751ff39 .ctaButton { background-color: #7F8C8D!important; color: #2980B9; border: none; border-radius: 3px; box-shadow: none; font-size: 14px; font-weight: bold; line-height: 26px; moz-border-radius: 3px; text-align: center; text-decoration: none; text-shadow: none; width: 80px; min-height: 80px; background: url(https://artscolumbia.org/wp-content/plugins/intelly-related-posts/assets/images/simple-arrow.png)no-repeat; position: absolute; right: 0; top: 0; } .uf67cce27fcdf147f87179a4f0751ff39:hover .ctaButton { background-color: #34495E!important; } .uf67cce27fcdf147f87179a4f0751ff39 .centered-text { display: table; height: 80px; padding-left : 18px; top: 0; } .uf67cce27fcdf147f87179a4f0751ff39 .uf67cce27fcdf147f87179a4f0751ff39-content { display: table-cell; margin: 0; padding: 0; padding-right: 108px; position: relative; vertical-align: middle; width: 100%; } .uf67cce27fcdf147f87179a4f0751ff39:after { content: ""; display: block; clear: both; } READ: Richard Avedon: Changing The Future Through Art EssayThis is not peace. This is violence. Its what mercenaries do. It turns out that the ones with the biggest mouths didnt put up much of a fight while being evicted from the occupied territories. Hmm. All this religious fundamentalism is simply an inability to understand and/or to accept that the Haskalah requires the relinquishment of certain antiquated pathos; to free people from a hermetically sealed environment and to thus allow them to participate in the world at large, with free will, openly, and without fear of stigma or being ostracized. For how is it possible to share the light in a fundamentalist environment? By its very nature fundamentalism is cut off from outside influence thus intensifying the spectrum of intolerance because its standards are pre-set. When misused, the Masada consciousness always leads to trouble. Yeshayahu Liebowitz, the beloved Israeli philosopher once wrote The newly occupied territories would become an untenable burden for the country because they would force Israel to become a repressive society. His prediction came true, and the disengagement is proof of that. Too bad he didnt live to see it.

The Role of Consumer Protection Agency and the Judiciary on Consumer Protection free essay sample

A consumer can be defined as someone who acquires goods or services for direct use or ownership rather than for resale or use in production and manufacturing. Consumer protection  consists of laws and organizations designed to ensure the rights of consumers as well as fair trade competition and the free flow of truthful information in the marketplace. The laws are designed to prevent businesses that engage in fraud or specified unfair practices from gaining an advantage over competitors and may provide additional protection for the weak and those unable to take care of themselves. Consumer protection laws are a form of government  regulation  which aims to protect the rights of  consumers. For example, a government may require businesses to disclose detailed information about products—particularly in areas where safety or public health is an issue, such as food. Consumer protection is linked to the idea of consumer rights (that consumers have various rights as consumers), and to the formation of  consumer organizations, which help consumers make better choices in the marketplace and get help with consumer complaints. We will write a custom essay sample on The Role of Consumer Protection Agency and the Judiciary on Consumer Protection or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Other organizations that promote consumer protection include government organizations and self-regulating business organizations such as consumer protection agencies and organizations, the Federal Trade Commission etc. Consumer interests can also be protected by promoting competition in the markets which directly and indirectly serve consumers, consistent with economic efficiency. In Nigeria, the major Consumer Protection Agency saddled with this responsibility is the Consumer Protection Council (CPC). Consumer Protection Council (CPC)  is a Parastatal of the Federal Government of Nigeria, supervised by the Federal Ministry of Trade and Investment. Though established by Act No. 6 of1992, it commenced operations only in 1999, when its institutional framework was put in place. The mandate of CPC is to, among others, eliminate hazardous products from the market, provide speedy redress to consumers complaints, undertake campaigns which would lead to increased consumer awareness, ensure that consumers’ interest receive due consideration at the appropriate forum, and encourage trade, industry and professional associations to develop and enforce in their various fields uality standards designed to safeguard the interest of consumers. While using all legitimate means to eliminate the scourge of consumer rights abuse in the Nigerian market place, it is common knowledge that an uninformed consumer population cannot be effectively protected if they do not know that they have rights, what the rights are, and how the rights could be protected. On the other hand, businesses and organizations also need to be well acquainted with their obligations to consumers. Based on this, the CPC serves to effectively police the market, sensitizing consumers to their rights and responsibilities and at the same time ensuring that businesses are committed to fulfilling their obligations to consumers. This is all in a bid to ensure that the country would become a better consumer-friendly nation. Consumers are entitled to a variety or rights, and the Consumer Protection Council and other consumer protection agencies serve to create awareness of these rights. All of which must be insisted upon, and most of which are stated below: 1. The Right to Satisfaction of Basic Needs: Access to basic goods and services necessary for survival, such as food, water, energy, clothing, shelter, health-care, education and sanitation. Goods and services must meet the standard of quality promised such that there is value for money in the purchase. 2. The Right to Safety: Protection from hazardous products, production processes and services. The Right to Information: Provision of information enabling informed consumer choice as well as protection from misleading or inaccurate advertising and labeling. 4. The Right to Choose: Access to variety of quality products and services at competitive prices. 5. The Right to Redress: Compensation for misrepresentation, shoddy goods and unsatisfactory public and private services, including the right to adequate legal representation. 6. The Right to Consumer Education: Acquisition of the skills required to be an informed consumer throughout life. 7. The Right to Consumer Representation: Advocacy of consumers interest and the ability to take part in the formulation of economic and other policies affecting consumers i. e. the right to be heard. 8. The Right to a Healthy Environment: Habitation is a place that is safe for present and future generations and which will enhance the quality of their lives. On its own part, the Judiciary is defined as the system of courts of justice in the country, and serves to ensure that all laws regarding consumer protection are enforced and strictly adhered to, and stiff penalties are meted out to defaulters. The laws, terms and conditions regarding consumer protection are reflected in The Consumer Protection Council Act (1992 No 66), where control of key aspects of consumer protection such as sales promotions, advertisements, products and services monitoring and regulation are explicitly stated. For instance, in the case of sales promotions, The Consumer Protection Council Act grants authority to the CPC to verify the genuineness of all sales promotions, ensuring that they are within legal, decent, honest and faithful limits, and ensure their direct supervision. The judiciary metes out penalties to erring parties which could be in the form of suspension for a definite period of time, fines and/or direct prohibition of activity. These, to a large extent are aimed at regulating and controlling the excesses of manufacturers, advertisers and consumers and ensure that all practices concerned are within legal and permissible limits, and is especially necessary in countries such as Nigeria because the global crisis has made ready markets in developed countries to look for emerging markets with a huge population base to dump their products, and Nigeria fits the description of such emerging market. The judiciary, through the enforcement of The Consumer Protection Council Act (1992 No 66), which guides consumer protection, ensures that Nigeria does not become a ready market for unscrupulous foreign countries and companies to dump products and services.

Athenian daily life essays

Athenian daily life essays In Ancient Greece, boys go to school, while the girls stayed at home to help their moms cook and look after the household. In Athens, it was a man's world. In the family, the father was the head of the family. The wife stayed at home and ran the household. The husband could divorce, if the wife was unfaithful or had no children. The marriage was arranged by the father or a close male relatives or guardians. For women life didnt extend far from the home, which was thought to be their sole realm of existence. Though they ranked higher than slaves did, they were treated in many of the same ways. Just like slaves, their mothers trained women as adolescents what their domestic duties were. They were secluded from all males, including those in their family. The main purposes are to have children to continue the family name and to honor the parents. Athenian women had virtually no political rights of any kind and were controlled by men at nearly every stage of their lives. Since men spent most of their time away from their houses, women dominated Athenian home life. The wife was in charge of raising the children, spinning, weaving, and sewing the familys clothes. She supervised the daily running of the household. In a totally slave based economy, ample numbers of female slaves were available to cook, clean, and carry water from the fountain. Only in the poorest homes was the wife expected to carry out all these duties by herself. In a sense, poor women lived freer lives than that of the aristocratic women they served. They could work in the fields or sell in the marketplace, pretty much going about their way as men did. (McKay page 76) The Greeks were polytheistic people. Meaning they believed in more than one god. Its impossible to say exactly how many gods there were because different Greeks worshiped different gods and some small villages worshiped the main gods and their own village gods. There are hund...

Dynamic Character vs. Static Character How Are They Different

Dynamic Character vs. Static Character How Are They Different Dynamic Character vs. Static Character: How Are They Different? A common piece of criticism you'll hear in fiction is that characters are "too static." Modern audiences can tell when a character isn’t interesting or realistic, based on their own lack of emotional investment in that character’s journey. As a result, authors feel compelled to ensure that their protagonist is a dynamic character - and that many of their other characters are, too.And we want to help them out! Which is why in this article, we'll take a look at the different types of dynamic characters and how authors can write them into their books. We'll also examine static characters and why authors should avoid them most (but not all) of the time.As a fun bonus, we've created an exciting new infographic that illustrates three common narratives associated with these characters. To jump straight to the infographic, click on Infographic: "The Book Deal" in the table of contents to your left! You can also watch our video on how to create dynamic characters below. Otherwi se, let's dive in. What is a dynamic character?A dynamic character  is a character who undergoes substantial internal change - in personality, attitude, or worldview - over the course of the narrative. This change usually happens gradually, though sometimes a character will have a revelation that changes everything about them very suddenly.Most well-developed characters are naturally dynamic. After all, characters who don't change at all typically don't have book-worthy adventures. And no matter what the story, readers almost always prefer reading about dynamic characters over static ones. That's why some of the most classic tales of all time feature distinctively dynamic protagonists: Ebenezer Scrooge, Elizabeth Bennet, Don Quixote, the list goes on and on.Keep in mind that protagonists, antagonists, and minor characters can all be dynamic. For the sake of focus, this article deals with main characters. However, everything we cover re: how to write a dynamic protagonist can also apply to supportin g characters. Ebenezer Scrooge - one of the most famous dynamic protagonists ever. (Image: Walt Disney Studios)The difference between "dynamic" and "well-rounded"Many people mistakenly believe that a dynamic character is exactly the same as a well-rounded character. But "dynamic" simply means that the character changes, while "well-rounded" means that they're fleshed out with a backstory, motivations, strengths, weaknesses, etc.There's a great deal of overlap, and most well-written protagonists are both dynamic and well-rounded. However, it's possible to have a character that changes throughout the story, but otherwise lacks substantial development (though this is a pretty unusual occurrence).You'll more commonly see well-rounded characters who change very little (if at all) in a story - usually to serve as a constant for another character. For example, in To Kill a Mockingbird, Atticus Finch is clearly well-rounded. But that doesn't mean he's dynamic; indeed, his attitude and views remain the s ame through the story. His steadfast morality serves to teach his daughter, Scout, about right and wrong. Consequently, she is the dynamic protagonist, while he facilitates that change. Dynamic character = well-rounded character: true or false? Find out here! What is a static character?As you might expect, a static character does not develop or change throughout a narrative. Their beliefs do not evolve, their personalities remain the same, and their worldview does not expand or adapt whatsoever.So why do static characters even exist? The answer is twofold. Firstly, static characters exist because not all authors know how to write a good character arc. Particularly in shorter pieces of fiction, you'll often see a character who seems  like they should undergo some kind of development or change, but ultimately doesn't.But secondly, sometimes static characters are written that way intentionally, to make a point or poke fun at a certain type of person. For example, Mr Collins in Pride and Prejudice is a static character. However, he acts as an example of a silly society man, and his foolishness and pomposity contrast humorously with Lizzy's perceptive wit.Static characters may be used as foils or even enemies to the dynamic protagonist, such as the Dursleys in Harry Potter, or just about every Disney villain ever. Finally, static characters can sometimes be positively symbolic or instructive, as in the TKAM example above. But this is relatively rare compared to the other types of static characters, who tend to be stupid and/or malevolent.The important thing to remember about static characters is that they should almost always be accompanied by dynamic characters. Dynamic characters give static characters purpose; without them, our static friends would just be languishing in a plotless wasteland. The sole exception to this rule is satire - if the entire story functions as a critique, all the characters may be unchanging in order to demonstrate their unintelligence or weakness. The wicked stepsisters are static character "foils" to the sweet, kind Cinderella. (Image: RKO Radio Pictures)How to write a dynamic characterIn a creative writing course, you could spend weeks learning different approaches for writing dynamic characters. This guide won't provide you with "the key" to creating a dynamic protagonist, but it will offer questions and considerations to guide you toward that goal.We also won't talk about how to write static characters, as you want to avoid them most of the time. However, if you're hoping to create a static character to serve some significant purpose in your story, know that most of the steps are basically the same - you'll just stop short of actually setting them on a journey.We recommend downloading this free character profile template before you start. Then read on for some helpful tips!Character creationThe first step to writing  any  character, but especially a dynamic one, is to get their essentials down first. For this, many au thors find it useful to create a character sheet. This is  a little dossier that answers some basic questions about each individual in your story, both physically and personality-wise.So let's say your protagonist is a doctor. Her character sheet might answer these questions:What kind of medical school did she go to, and what kind of student was she?How is her relationship with her family? Does she currently have a partner?What is her religious faith and how does it affect her work (if at all)?Does she have any bad habits  or strange quirks?How self-conscious or confident is she?How frugal is she with her money?And so on. The answers to these questions might not always make it onto the page, but knowing even seemingly inconsequential details about your characters can have a big impact on your story. These kinds of character development exercises really help build believable people to populate your book - characters who readers want to follow, even before they begin to change.Ch aracter motivationAnother critical component of dynamic character creation is  motivation.  In order for a protagonist to go on a journey of self-discovery, they have to pursue something that they want, need, or are otherwise compelled toward.For instance, your main character might be a jet-setting career man who wants romance and a family; an army medic who wants to survive the war; or a retired gunslinger who wants to be left alone. This desire don’t have to be grand and philosophical! There have been great stories told about no more than a young boy who wants a new pair of shoes. There's that retired gunslinger. (Image: Warner Bros)A protagonist’s desires will become a driving force in the story. How close or far a character comes to achieving a goal creates tension and moves their journey along. Typically, in order to change, a character must either A) reach their goal, or B) fail to do so, but realize something greater in the process.Here are a few questions to help you determine your characters' motivations and trajectories:Will the character get what they  want, but at a dear cost?What personal obstacle(s) must they overcome before the desire is reached/obtained?How will securing this goal - or failing to do so - alter them as a character?What if your protagonist’s greatest desire is simply impossible?Internal character conflictWhile conflict is often interpreted as "protagonist vs. antagonist," it’s far more important to consider a character’s internal conflict. When telling the story of your character’s personal jo urney, it's important for them to encounter conflict, as they  themselves  hinder their own success. Here are a few examples of dynamic characters' inner conflicts to show you what we mean:Dumbo is a story about fighting fears and self-doubt. Dumbo’s buddy, Timothy Mouse, gives him a "magic feather" to help him fly. He loses this feather in the final scene, and must overcome his internal fear and self-doubt to save the circus.In Great Expectations, it is only when Pip realizes his worldview has been wrong - that Miss Havisham is not his benefactor, that Estella has not been promised to him, and that he has treated his closest friends and family terribly in order to "become a gentleman" - that he can start to make things right.Elizabeth Bennet has feelings for Darcy, but before she can find happiness, she must overcome her own wounded pride. Likewise, Darcy must grapple with his class-bred prejudices before he can successfully woo Ms. Bennet. These internal conflicts are the essence of Pride and Prejudice.Before you write your first draft, consider how your protagonist’s flaws or specific worldview will work as an obstacle between them and their goal. Likewise, consider how the resolution of these issues will bring your protagonist closer to their desires - and ultimately to a different state of being.Use external conflict to show internal strugglesMost novels can’t unfold in an entirely internal, psychic landscape. Authors need to find ways to move their protagonists through time and space as they undergo internal changes. In other words, you have to show character development via external conflict, instead of just letting characters sit around thinking about self-improvement 24/7.Jay Gatsby’s extravagant parties and upper-class affectations show his desire to rewrite his history and transcend the American class system. If Gatsby’s fatal flaw is his refusal to accept that the past is past, the external conflict that re flects plays out in his pursuit of and affair with Daisy, and the fatal repercussions it has.Fitzgerald more extensively shows this conflict by putting Gatsby at odds with Tom Buchanan. A cruel, unlikable figure, Tom is nonetheless everything Gatsby aspires to: an old-money WASP married to Daisy, Gatsby’s childhood crush. But because Gatsby cannot turn this desire into a change he can actually make - i.e., he can't go back in time and change the circumstances of his birth - he becomes increasingly desperate, careless, and ultimately meets his karmic maker. Jay Gatsby, Daisy Buchanan, and Tom Buchanan from The Great Gatsby (Image: Warner Bros)Can they change for the worse?Growth is subjective, as is morality. Characters sometimes fall to the "dark side" over the course of a story, like Walter White in TV’s Breaking Bad. Walter White is a family man and high school chemistry teacher with terminal cancer. To make money before his death, he starts manufacturing drugs and becomes involved with the criminal underworld.Over the course of the series, Walter White's morality is put to the test in ever more extreme ways. Each external conflict Walter faces has an internal result, and throughout the series we watch him toe the line between good and evil. His original intentions - to protect his family even after his death - are noble, but his means to this end are nefarious. As a result, Walter must â€Å"break bad† in what has become a modern exemplar of character evolution.But what if the protagonist doesn’t really change ?If the mark of an interesting lead character is their personal growth, then their story will chart a journey from the person they were in chapter one to the person they are on the final page. But surely there are plenty of compelling characters who encounter conflict, yet do not change all that much over the course of a narrative?As we've discussed previously, it's definitely possible for a character to be well-rounded without changing very much. But what about a main character? Let's look at a few examples here.From the outside, Katniss Everdeen in The Hunger Games wouldn’t be your first example of a dynamic character. She starts out courageous, resourceful, and principled, and stays that way throughout the story. Even after the Games put her ideals to the ultimate test, it's only through her selflessness and resourcefulness can she beat the system and leave with them intact.In Andy Weir’s The Martian, supremely chill botanist Mark Watney is trapped on Mars. He quick ly realizes that only his ingenuity and knowledge of science can save him. He encounters a chain of disasters that threaten to break his resolve. Instead of finding some internal flaw that needs resolving, it’s only by maintaining his trademark cool and returning time and again to science, that Watney is able to escape the Red Planet. Matt Damon as Mark Watney in The Martian (20th Century Fox)Don't worry: they're still dynamicBoth Katniss and Mark Watney find the strength to survive by sticking to their guns and having faith in their beliefs. But this doesn't mean they haven't changed at all - it's just that the primary change they've undergone is a strengthening of their core beliefs, rather than a fundamental alteration. They also experience smaller, more subtle changes, such as becoming more hardened to their surroundings and wary of danger.In other words, Katniss and Watney aren't what you'd call "exemplary" dynamic characters, but they're not static characters either. And clearly their journeys were compelling enough to engage readers, since both The Hunger Games  and  The Martian  became mega-hit bestsellers and blockbuster movies!Speaking of which, let's take a look at this awesome infographic (featuring some of your favorite characters) to really nail down the arc of a dynamic character.Infographic: "The Book Deal" Infographic: What does a dynamic character's arc look like? To see how a protagonist's wants, strengths, and flaws will  influence  how a story plays out, we took three familiar characters and placed them in an unfamiliar setting. Let's see how they develop over the course of a  narrative: Failure to change results in tragedyWhen your protagonist grapples with inner and outer conflict,  but fails to adapt, they are almost always punished - by themselves, another person, or the universe. This is what we call  tragedy.In Cyrano de Bergerac,  the titular character is in love with Roxane. However, his self-doubt prevents him from revealing that he has written the words that have won her heart. Cyrano does not overcome this doubt in time, and becomes mortally injured before Roxane realizes that she loves him.And in an example we've already covered, Jay Gatsby learns too late that â€Å"there are no second acts in American lives.† He wants to force his way into the upper classes, but he’s unable to see that this world will not allow him in. He refuses to divert his course so, in the end, we find him bleeding out, alone, in his swimming pool.Both of these characters encounter conflict and grapple with their flaws in a fascinating way. But in the end, thei r failure to change themselves results in their tragic deaths.How much change is too much?Assuming you want your book to remain within the realm of believability, your character’s change should be relatively small. Human beings are capable of great change, but only a bit a time.Again, Ebenezer Scrooge is perhaps the most classic example of a dynamic protagonist. But if we’re being honest, the man at the end who buys 300-pound turkeys for the poor does not remotely resemble the penny-pinching miser in the first scene. However, nobody questions the psychological truth of Scrooge’s overnight transformation because A Christmas Carol is a moralist fable. It's not meant to be realistic, only to instruct.That said, if you’re writing a modern series, you should also be conscious of changing your characters too quickly or drastically. Let’s say that your breakout character is an irreverent, womanizing highwayman. You can have him confronted by a victim of h is crime or philandering - something that forces him to reassess his lifestyle choices.Yet you don’t want him to learn too much. Otherwise you run the risk of turning your series into the ongoing narrative of a former highwayman, who now very much respects property rights and does not flirt with women quite so aggressively. The key is balance: don't stray too far from your character's original personality, but allow them to change in an organic way, at a reasonable pace.Remember: there's no formula for great charactersShould your story not follow one of these common patterns, you may find it’s harder to nail down exactly how internal flaws and external conflicts play out over the course of your book. But even in unconventional narratives, always remember to think of the basics: What does your character want? What’s stopping them from getting it? And will they find the strength to change? These questions will help you - and your characters - find the right way .If you have any questions, thoughts or observations, please share them in the comments below.

Discovery in the Amazon Case Study Example | Topics and Well Written Essays - 500 words

Discovery in the Amazon - Case Study Example It can also be speculated that the pipeline will give rise to cases of dispossession. The orthodox frame might argue that the pipeline will finally help in the integration of the tribes into the market economy and thus introduce them to the benefits o the development, but a more critical perspective would go further and question, â€Å"what/who has kept them out?† – thus referencing a historical divergence point that has created a global system wherein the wealth of one class limits the development possibilities of the other. In diametric opposition to the claim that it was the birth of capitalism (and the ability to produce capital) that was the turning point in the West and what freed people from poverty, there are arguments that the beginnings of formal property rights was what led to the extinction of customary and collective rights and the deprivation of access to land and other resources of the marginalized. And while the Capitalist-driven frame traces the roots of poverty to the existence of barriers to the market exchange of land and resources, the counter-frame questions the logic of this commodification and exposes the flaws of an unfettered market exchange. This would result in a slew of other human rights violations such as food sovereignty and land sovereignty. Moreover, there is a clear violation of the autonomy and self-determination of the indigenous tribes that occupy the areas in Ecuador to be affected by the pipeline. Western thought has cultivated the notion that there is but one trajectory towards progress and development, and this can be quantified in material terms. Development, according to Western thought, means roads and infrastructure, access to markets and trading, a quality life that approaches, if not approximates Western life as it is known. But this kind of thinking is in itself an imposition of a Western imaginary that obscures equally legitimate ways of living and